بیوتکنولوژی - BIOTECHNOLOGY

A Virginia Tech research group lead by two biochemistry graduate students has isolated proteins responsible for the iron-sulfur cluster assembly process and witnessed the necessary protein interactions in vivo -- within a cell. They have captured pathway intermediates and observed protein interactions between the two major players in iron-sulfur cluster assembly.

Click on the ( ادامه مطلب)  for continue and Click on the (نظر دهید) for comment

به گزارش رويترز از واشنگتن، اين پژوهشگران تاکيد کردند که ناموفق بودن واکسن "ميرک" در سال گذشته نشان‌دهنده لزوم مطالعات سريعتر و با تمرکز بيشتر بر روي موضوع است.
"موسسه ملي آلرژي و بيماري‌هاي عفوني" آمريکا که بخشي از "موسسه ملي بهداشت و سلامت" آمريکا است، روز پنجشنبه اعلام کرد که مطالعه واکسن ايدز موسوم به "پيو - ‎ (PAVE 100) "100را لغو مي‌کند....

 International research group led by Yasushi Okamura, a professor in Japanese National Institute for Physiological Sciences, Okazaki, and Peter Larsson, a professor in Oregon Health & Science University, Oregon, US, found that a single protein of VSOP, Voltage Sensor Only Protein/ Hv1, can carry protons even without making a multimeric complex.

Click on the ( ادامه مطلب)  for continue and Click on the (نظر دهید) for comment

 به گزارش خبرگزاري فرانسه، داروي ديمبون Dimebon نخستين بار در سال 1983 کشف شد و در روسيه بعنوان داروي آنتي هيستامين به فروش رفت. اما ورود داروهاي بهتر به بازار، از ارزش کارايي آن کاست. چند سال پيش، زماني که بررسي هاي آزمايشگاهي محققان فرهنگستان علوم روسيه نشان داد اين دارو تاثير محافظتي بر روي سلول هاي مغزي دارد، اين دارو مورد توجه قرار گرفت....

Snakes, fish, chickens, and humans all begin life in much the same way. Early in their transformation from an amorphous blob of cells into a fully developed animal, growing cells pinch off into a string of identical segments destined to become individual vertebrae, which will later sprout blood vessels, peripheral nerves, and muscle. These repeated segments ensure that the rod-like spinal column can hunch, arch, and twist.

Click on the ( ادامه مطلب)  for continue and Click on the (نظر دهید) for comment

MIT researchers have figured out how bacteria ensure that they respond correctly to hundreds of incoming signals from their environment.

Click on the ( ادامه مطلب)  for continue and Click on the (نظر دهید) for comment

اين پژوهشگران اعلام کرده اند که فلفل تند مي تواند مانع از رشد سلول هاي سرطاني در مبتلايان به سرطان پروستات و عاملي در درمان اين بيماري باشد. اعضاي گروه تحقيقاتي در مرکز پزشکي سيدار سينا در لس آنجلس، آمريکا، اعلام کرده اند که آزمايش هاي انجام شده روي موش هاي آزمايشگاهي و همچنين سلول هاي پروستات مبتلايان به سرطان پروستات نشان مي دهد که ماده شيميايي کاپسايين، عامل تندي ميوه فلفل، به نابودي سلول هاي سرطاني منجر مي شود.

Interactions Within Membrane Complexes Can Be Maintained In Vacuum Of Mass Spectrometer

Against currently held dogma, scientists at the Universities of Cambridge and Bristol have revealed that the interactions within membrane complexes can be maintained intact in the vacuum of a mass spectrometer. Their research was recently published in Science Express.

Click on the ( ادامه مطلب)  for continue and Click on the (نظر دهید) for comment

«اين پترسون» از دانشگاه ايالتي ميشيگان و «موريس ولان» از مرکز تحقيقات مشترک DG کميسيون اروپا هنگام تصويربرداري از سلول‌ها، اين ايده به ذهن‌شان خطور کرد. اين دو نفر دريافتند که Caustics (نور بسيار روشني که ازيک سطح منحني در اثر شکست يا انعکاس ساطع شده و يک سايه را احاطه مي‌کند)، تصاوير با تفکيک‌پذيري بالاي ميکروسکوپ آنها را مختل مي‌کند...

Duke University Medical Center scientists have found a mechanism that allows cells starved of iron to shut down energy-making processes that depend on iron and use a less efficient pathway involving glucose. This metabolic reshuffling mechanism, found in yeast cells, helps explain how humans respond to iron deficiency, and may help with diabetes research as well.

Click on the ( ادامه مطلب)  for continue and Click on the (نظر دهید) for comment

How does a stem cell decide what specialized identity to adopt -- or simply to remain a stem cell? A new study suggests that the conventional view, which assumes that cells are "instructed" to progress along prescribed signaling pathways, is too simplistic. Instead, it supports the idea that cells differentiate through the collective behavior of multiple genes in a network that ultimately leads to just a few endpoints -- just as a marble on a hilltop can travel a nearly infinite number of downward paths, only to arrive in the same valley.

Click on the ( ادامه مطلب)  for continue and Click on the (نظر دهید) for comment

                          AZAD ISLAMIC UNIVERSITY ZANJAN

احدی خاطرنشان کرد: موضوع تحقیق من "جداسازی و تعیین صفات اختصاصی باکتریهای تجزیه کننده آلاینده فنل از خاک، نفت و پسابهای آلوده" است و فعالیت در این زمینه از شهریور ماه سال 86 شروع شده است.وی گفت: برای این تحقیق که منجر به کشف باکتری جدیدی شد نمونه ای از چاه نفت آبادان تهیه شد که حاوی باکتری بومی بود و تا به حال شناسایی نشده بود.احدی ادامه داد: از خصوصیات این باکتری این است که قادر به تجزیه فنل است در حالی که فنل یک ترکیب آروماتیک است که باعث سمی شدن آبها به خصوص آب های زیرزمینی و آب دریاها می شود....

                                               BIOLOGY LABORATORY   

 A team of scientists has provided, for the first time, a detailed map of how the building blocks of chromosomes, the cellular structures that contain genes, are organized in the fruit fly Drosophila melanogaster. The work identifies a critical stop sign for transcription, the first step in gene expression, and has implications for understanding how the AIDS virus regulates its genes. The findings will be published in the 15 May 2008 issue of the journal Nature.

Click on the ( ادامه مطلب)  for continue and Click on the (نظر دهید) for comment

 Researchers in Korea report development of a way to double production of a sticky protein from marine mussels destined for use as an antibacterial coating to prevent life-threatening infections in medical implants. The coating, produced by genetically-engineered bacteria, could cut medical costs and improve implant safety, the researchers say.

Click on the ( ادامه مطلب)  for continue and Click on the (نظر دهید) for comment

 A study performed by researchers at the Institute for Research in Biomedicine (IRB Barcelona) on the fruit fly, Drosophila melanogaster, unveils how distinct signaling pathways operate between neighboring cells in order to activate the cell proliferation machinery that results in the organized growth of the fly wing. The signaling pathways involved in this process are also conserved in humans, and when altered in diverse tissues give rise to the appearance of different types of cancer, including cancer of the colon and skin, and leukemia. The study has been undertaken in the Cell and Development Biology Laboratory headed by ICREA Research Professor, Marco Milán, at IRB Barcelona.

Click on the ( ادامه مطلب)  for continue and Click on the (نظر دهید) for comment

Using artificial sugar and some clever chemistry, University of California, Berkeley, researchers have made glow-in-the-dark fish whose internal light comes from the sugar coating on their cells

Click on the ( ادامه مطلب)  for continue and Click on the (نظر دهید) for comment

Using an enzyme of the Japanese mushroom Grifola frondosa (Maitake or dancing mushroom), proteins can be identified without knowing the organism's genetic composition. This advance simplifies the study of proteins lying at the root of such diseases as cancer and diabetes. Utrecht University Prof. Albert Heck's research group announced this breakthrough on the website of the journal Nature Methods.

Maitake mushrooms. Using an enzyme of the Japanese mushroom Grifola frondosa (Maitake or dancing mushroom), proteins can be identified without knowing the organism's genetic composition. (Credit: iStockphoto/Laryn Bakker)

Click on the ( ادامه مطلب)  for continue and Click on the (نظر دهید) for comment

Researchers at the University of Illinois at Chicago have discovered how some bacteria can survive antibiotic treatment by turning on resistance mechanisms when exposed to the drugs. The findings, published in the April 24 issue of the journal Molecular Cell, could lead to more effective antibiotics to treat a variety of infections.

                                             yersinia fluorescent antibody  

Click on the ( ادامه مطلب)  for continue and Click on the (نظر دهید) for comment